first_imgWolves boss Nuno left frustrated after Southampton drawby Paul Vegas6 days agoSend to a friendShare the loveWolves boss Nuno was left frustrated after their 1-1 draw with Southampton.The visitors went ahead in sloppy circumstances from a Wolves perspective, as Danny Ings capitalised to slot home. Wolves showed the spirit to come back and equalise through Raul Jimenez’s penalty, and Nuno wants his team to learn from their performance and build on an improved second-half.He said, “I’m disappointed because one of the things we are, and must be, is solid and today we were not. Sometimes you have to stay in the game, Southampton broke us when we should be more solid in defence.“We created but not in the right areas we should. We played long, Southampton did very well, they pressed us very well, they were organised and are a very good team, they did a good job to make our task very hard in terms of possession of the ball.”He continued, “Sometimes it’s not what you want to do, it’s what the other team lets you do, but we should find better solutions. In the second-half we played better, we were more stable.“The goal we suffered was a mistake, we had to react, and we reacted OK, and then we pushed until the end.“It was not an easy game, it was a very tough game. It was very disrupted, not both teams controlling the game, we had an injury and didn’t play the way we should and could.“The game was very hard, we made mistakes, a lot of things happened in the game, so we have to improve for the next one.” About the authorPaul VegasShare the loveHave your saylast_img read more


first_imgFred Hoiberg dances in new Infiniti comemrcial.YouTubeWith the elimination of the Chicago Bulls from the NBA Playoffs, all signs point to the franchise parting ways with head coach Tom Thibodeau. Who will take over the historic franchise if the job opens up as expected? According to Yahoo Sports’ NBA insider Adrian Wojnarowski, Iowa State head coach Fred Hoiberg is the only coach on the Bulls’ list.“The job will be Fred Hoiberg’s if he wants it,” Wojnarowski said. “There’s not going to be any competition for him. Now, it’s conceivable that Fred Hoiberg decides to stay at Iowa State, but if they make a change and Tom Thibodeau is out, Fred Hoiberg is really the only candidate for this job from the Bulls perspective. But that doesn’t guarantee that he’s going to do it. I know he’s already had to give it thought because it’s real.The full interview with Wojnarowski is available at CBS Chicago.Last week, Iowa State athletic director Jamie Pollard admitted that the NBA is likely in Hoiberg’s future.Jamie Pollard on Hoiberg/NBA rumors: “He has always said from Day 1 that his lifelong goal has been to coach in the NBA…” (1/2)— Travis Hines (@TravisHines21) May 12, 2015Pollard: “…It’s for him to decide when that part of his life he wants to activate.” (2/2)— Travis Hines (@TravisHines21) May 12, 2015I asked Jamie Pollard if he expected Fred Hoiberg to be his men’s basketball coach on Aug. 1: “I hope so.”— Travis Hines (@TravisHines21) May 12, 2015 Will the chance to coach Derrick Rose, Jimmy Butler, and Joakim Noah lead him out of Ames? We’ll probably find out pretty soon.[CBS Chicago]last_img read more


first_imgHan Geng, the singer, dancer and actor known as ‘the most influential male celebrity in China’ delivered last Saturday a speech that motivated the new generation of aspiring Chinese business leaders.Han Geng at LSBF Hope EventCredit/Copyright: LSBFHundreds of fans were inspired by the words of one of the most famous and influential Chinese men of our time. The event was hosted in support of the LSBF HOPE Foundation, a charity which aims to give young people the chance to achieve their dreams and career goals.Known as “King of Popularity” and having won the MTV’s EMA ‘Best Worldwide Act’, Han Geng is one of the most influential artists in China. During his speech, Han Geng showed how his way to the top was a story of struggle, fighting and striving to succeed overseas. His fans were able to discover the “man behind the success” and be inspired by Han Geng’s story.The event was hosted at the Westminster Central Hall, one of the most impressive venues in London. Before Han Geng’s speech, the audience had the chance to listen to the Director at LSBF School of English, Fay Drewry, who spoke about the challenges of studying and living in a foreign country, and the importance that English plays in the world today. The audience also watched a fashion show with the creations of students from the London College of Contemporary Arts and from the School of Fashion and Design London.Han Geng was received at the stage by LSBF’s Rector and CEO, Professor Maurits Van Rooijen, who presented him with an Award of Appreciation for his support to the LSBF HOPE cause.Members of the LSBF Board were at the event giving students the chance to learn more on how investing in education can help them to achieve more and take their careers further.The entire amount raised with donations at the event will be reverted to LSBF HOPE Foundation, which will be used for investing in charity schools in China.If you would like to learn more about how to develop you career with LSBF, click here.last_img read more


first_img Source:http://www.imperial.ac.uk/news/189417/bacterial-sleeper-cells-evade-antibiotics-weaken/ Reviewed by Alina Shrourou, B.Sc. (Editor)Dec 7 2018New research, from scientists at Imperial College London, unravels how so-called bacterial persister cells manipulate our immune cells, potentially opening new avenues to finding ways of clearing these bacterial cells from the body, and stopping recurrence of the bacterial infection.The latest findings, published in the journal Science, may help explain why some people suffer from repeated bouts of an illness, despite taking antibiotics. In the study, funded by the Medical Research Council, the Lister Institute and EMBO, the scientists, studied bacterial cells of Salmonella called persisters.Whenever bacteria such as Salmonella invade the body, many of the bugs enter a type of stand-by mode in response to attack by the body immune system, which means they are not killed by antibiotics.These bacteria persister cells stop replicating and can remain in this dormant, ‘sleeper-cell’ state for days, weeks or even months. When antibiotic treatment has been stopped, if some of these bacterial cells spring back to life, they can trigger another infection.Dr Sophie Helaine, senior author of the research from the MRC Centre for Molecular Bacteriology and Infection in Imperial’s Department of Medicine explained: “Persisters are often the culprit for repeat or hard-to-treat infections. The classic scenario is a person suffers some type of illness – such as a urinary tract infection or ear infection, and takes antibiotics that stop the symptoms, only for infection to return a few weeks later.”These persister cells are formed when bacteria are taken up by macrophages, which are human immune cells that have a key role in protecting the body against infections by engulfing bacteria and viruses. Once inside the macrophage, the persister can exist in this state in which antibiotics can’t kill it for weeks, or even months.Persisters were discovered in 1944 and were thought to be dormant inactive bacteria lying low in the body, acting as time bomb for relapse.Related StoriesGrowth problems in preterm infants associated with altered gut bacteriaFinger-prick blood test could help prevent unnecessary antibiotic prescribing for patients with COPDOlympus Europe and Cytosurge join hands to accelerate drug development, single cell researchIn the latest research, the scientists reveal that the persisters, while hiding in the body’s immune cells, are actually able to weaken the killing ability of the macrophages.The work was conducted in collaboration with the Vogel lab at the Helmholtz Institute for RNA-based Infection Research in Germany, a site of the Helmholtz Centre for Infection Research.Dr Peter Hill, co-author of the research explained: “Previously, it was thought the persisters are completely dormant. However the reality we revealed here is much scarier. They chip away at the defenses from the inside, weakening the power of the macrophages – which are a key part of our arsenal against infection. This means that once antibiotic treatment stops, they might have created a much more favorable environment for another bout of infection, or even a completely new infection from another bacteria or virus.”Although scientists, studied Salmonella infection of mouse macrophages in this research, many types of bacteria that commonly cause illness are known to form persisters in humans, including E.coli and the bacillus responsible for tuberculosis and Salmonella itself.The scientists are now investigating whether there is any way of turning the tables against the bacteria, and if they can target the mechanism by which the persisters weaken our immune cells.Dr Helaine added: “Although these findings suggest the persisters have a more profound effect on our immune defenses than previously thought, they also reveal a potential bacterial weakness. Persisters are hard to treat as they are invisible to antibiotics, but it may be this mechanism of weakening our immune cells could be a vulnerability of these persisters. We could potentially target this mechanism, and more efficiently clear hard-to-treat infections.”last_img read more


first_img Source:http://www.bristol.ac.uk/news/2018/december/bmi-measure-of-good-health.html Reviewed by Alina Shrourou, B.Sc. (Editor)Dec 11 2018A new study from the University of Bristol supports body mass index (BMI) as a useful tool for assessing obesity and health.A simple measure based on weight and height, BMI is widely used to assess if a person is of a healthy weight. But its reliability as a health measure is often criticized, as it does not distinguish fat from muscle and does not tell us where body fat is stored.Using body scans from 2,840 young people aged 10 and 18 in Bristol’s Children of the 90s population study, researchers examined BMI findings against more detailed measures of fat.They studied the effects of total fat, along with fat in the trunk, arms and legs, on 230 different traits relevant to metabolism and future heart disease risk, such as cholesterol and blood pressure. These effects were compared with those seen when using BMI as a measure.Related StoriesChaos in the house and asthma in children – the connectionTrends in colonoscopy rates not aligned with increase in early onset colorectal cancerStudy reveals link between inflammatory diet and colorectal cancer riskThe study, published in the Journal of the American College of Cardiology, found that higher total fat at age 10 and 18 was associated with damaging levels of cardiometabolic traits such as higher blood pressure and adverse cholesterol and inflammatory profiles at age 18.Effects appeared to worsen with time and were driven most by fat stored and gained in the trunk, although gains in leg fat also appeared harmful. Carrying more lean mass (assessed here as anything in the body that that isn’t fat or bone) had less of an impact on traits and did not appear to protect against carrying more fat. Higher BMI showed similar effects as higher total and trunk fat, reflecting close overlap between these measures.Dr Joshua Bell, an epidemiologist at the University of Bristol who led the study, commented: “BMI is often criticized. Our study asked how useful it really is for detecting the health effects of obesity by pitching it against more objective body scan measures. We found that trunk fat is the most damaging to health, but that simple BMI gives very similar answers to more detailed measures. This is good news since BMI is widely measured and costs virtually nothing.””We’re now in a better position to understand obesity in the young thanks to participants of the Bristol-based Children of the 90s study – they, and all study participants, make new insights possible.””We now need to look at more detailed lean measures to see if other aspects protect against higher fat, and how this might differ between the sexes. This is more important than ever given stubbornly high rates of obesity worldwide.”last_img read more


first_imgImage Credit: Bondar Illia / Shutterstock In a study published in the Journal of Children and Media, the researchers found that grandparents of today are spoiling their grandkids by allowing them, while under their supervision, to spend longer periods of time using gadgets than their parents might otherwise allow. The researchers wanted to see if other caregivers of children influence how much screen time kids experience. By Angela Betsaida B. Laguipo, BSNJul 9 2019Grandparents may be spoiling their grandkids, allowing them too much screen time, according to a new study. A team of researchers found that grandparents may be fueling excessive device usage among kids, which has become a growing health concern worldwide. “Studies were mostly based on parents’ reports and ignored other major caregivers, particularly grandparents. Accordingly, this study offers a pioneer exploration of young children’s interactive and non-interactive media use under their grandparent’s care and the factors associated with extensive use,” the researchers explained in the study. Children spend half of their time on gadgetsThe researchers studied the grandparents’ experiences in taking care of children aged between 2 and 7 years old. They found that on an average of a visit lasting for 4 hours, the kids spent two hours either playing games on gadgets or watching videos.The results show that let the children spend about half of their time on a tablet, computer, television, or mobile phone.Study findings are alarmingBoys spend more time on gadgets than girls, with 17 minutes more screen time. Other findings show that the grandparents claim they feel less confident in supervising the gadget use of their grandkids than in handling their use of non-interactive videos.But, the results also show that grandfathers were more likely to allow more interactive screen time than grandmothers. Hence, the researchers suggest that they are more confident and knowledgeable in using technology.Related StoriesResearchers identify gene mutations linked to leukemia in children with Down’s syndromeNew therapeutic food boosts key growth-promoting gut microbes in malnourished childrenResearch reveals genetic cause of deadly digestive disease in childrenOlder children may spend more time on devices than younger ones, and grandparents were more likely to let their grandchildren spend more time on these gadgets if the parents gave instruction on how to use these technologies beforehand.  Plus, the grandparents let the kids play gadgets or watch videos when they look after the kids in their own homes than when they’re in the children’s houses. They also allow more time spent on gadgets when the kids ring their own device.Overall, the lowest amount of time dedicated to media use per visit with grandparents was seen among children who are 2 to 3 years old, with only 98 minutes per visit. On the other hand, children who are 4 to 5 years old spend about 106 minutes on gadgets. The age group show spent most screen time are those who are 6 to 7 years old.Grandparents should set screen time restrictions“Grandparents play a significant role in raising their grandchildren. We need to educate them about the impact of media on children’s lives and on proper use that will benefit the wellbeing of their grandchildren,” Dafna Lemish, study co-author, said in a statement.The researchers suggest that grandparents should play a part in teaching kids on responsible device use, by restricting media use. They can do this by setting simple rules on screen time when they are babysitting.Moreover, grandparents should set firm rules on screen time, which is not more than 1 hour, not during meals, and not before bedtime. This way, they can help reduce screen time among children. For parents, they should provide toys, books, and games to help grandparents babysit and keep the children busy.“These findings raise concerns regarding young children’s media use under their grandparents’ watch, but also suggest effective strategies for its reduction,” the researches concluded in the study.Health effects of too much screen time among childrenIn another recent study, children who spend more time on gadgets and devices are more likely to have health harms, including unhealthy diet, adiposity, depressive symptoms, and decreased quality of life.Other health problems include anxiety, depression, behavior problems, hyperactivity and inattention, low self-esteem, other mental health problems. Journal references: Elias, N., Nimrod, G., and Lemish, D. (2019). The ultimate treat? Young Israeli children’s media use under their grandparents’ care. Journal of Children and Media. https://www.tandfonline.com/doi/full/10.1080/17482798.2019.1627228 Stiglic, N., and Viner, R. (2019). Effects of screen time on the health and well-being of children and adolescents: a systematic review of reviews. BMJ Open Pediatrics. https://bmjopen.bmj.com/content/9/1/e023191last_img read more


first_imgDo you love music? Do you love science? Would you like to go to a festival where both are rolled up into a weekend of family fun? Well look no further, as we’re giving away four tickets (two adults plus two teens (11 to 15 years old) for a weekend of camping and festival-going at BlueDot festival, located at Jodrell Bank Observatory, Cheshire, United Kingdom. Kicking off on Thursday, July 18, this event will last through Sunday (July 21) and will be jam-packed with science, art and music in the most creative and immersive fashion. Not only will there be talks from the brightest scientists from around the globe, but there will be a selection of world-famous art on display. The main stage will sit in the foreground of the observatory’s Lovell Telescope, which has been at the forefront of scientific discovery for over half a century. Thursday will begin the long weekend of musical acts, including an opening convert from The Hallé. The kick-off will see music acts such as Hot Chip, Jon Hopkins, Kate Tempest and Ibibio Sound Machine, among many more. Saturday will welcome Kraftwerk 3-D, Jarvis Cocker, 808 State, Sons of Kemet and more. Finally, Sunday will finish with multiple award-winning New Order, John Grant, Gruff Rhys, Anna Calvi, Gogo Penguin and others.Headbutting Tiny Worms Are Really, Really LoudThis rapid strike produces a loud ‘pop’ comparable to those made by snapping shrimps, one of the most intense biological sounds measured at sea.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Why Is It ‘Snowing’ Salt in the Dead Sea?01:53 facebook twitter 发邮件 reddit 链接https://www.livescience.com/65823-win-tickets-bluedot-festival.html?jwsource=cl已复制直播00:0000:3500:35  But it’s not just the music that people travel from around the world to see, and this includes the brilliant scientists and engineers providing brilliantly informative talks about the latest in STEM subjects. Such names include Britain’s first astronaut Helen Sherman, famous science historian James Burke, French-Irish science and history presenter Liz Bonnin and other exciting names in the world of science, including Jim Al-Khalili, Dallas Campbell and the director of Jodrell Bank, Tim O’Brien. In between the music and the science, there are opportunities to visit some exciting stalls with a variety of interesting cuisines; there are comedy shows, stargazing, microbrewery, mixology, family events, a deep-space disco and so much more. *Please note that the ticket isn’t valid until 9 a.m. on July 19. To be in for the chance of winning tickets to an unforgettable weekend of science and music, all you need to do is enter here before the July 10.by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 min and see why everyone is addicted!Vikings: Free Online GameUndoTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndoKelley Blue Book2019 Lexus Vehicles Worth Buying for Their Resale ValueKelley Blue BookUndoAudie Murphy RanchGet more home without moving away from Southern CaliforniaAudie Murphy RanchUndoLivestlyThe List Of Dog Breeds To Avoid At All CostsLivestlyUndolast_img read more


first_imgPiyush Goyal, BJP’s election in-charge for Tamil Nadu, addressing the media in Chennai on Friday   –  Bijoy Ghosh poll campaign COMMENT COMMENTS ‘Gandhi family, DMK corrupt to the core’ People will do a ‘surgical strike’ on the DMK and the Congress because they are the fountain-head of corruption in this country, said Union Minister Piyush Goyal, who is BJP’s election incharge for Tamil Nadu, while reacting to Congress President Rahul Gandhi’s corruption charges on the BJP at a rally in Krishnagiri.Gandhi should first answer as to why his family and his party had allowed poverty in India for so many years while they were in power. “Three generations of Gandhi family rule had cheated the poor of India. Now, the poor of India don’t trust the Gandhi family, the Congress or the DMK because they make only false promises,” Goyal told newspersons here. Various corruption cases, including Coalgate, Aircel-Maxis; 2G and telecom (BSNL-Maran case), happened during the Congress rule in which the DMK was an alliance partner. “The nation wants to know whether they are going to do only corruption or will they ever think for the poor of India. Nobody believes their false promises,” he said.NDA in Tamil Nadu “I am confident that people here want Modi to once again become Prime Minister and serve the people of India,” Goyal said.In the 2014 Lok Sabha elections, all the 40 seats, including the lone Puducherry seat, were won by current NDA alliance partners — the AIADMK (37); the PMK (one); the BJP (one) and the NR Congress in Puducherry. This time, “we have formed the biggest alliance that Tamil Nadu has ever seen. We are confident that people here will support this alliance, which stands for strong, stable, decisive, honest and visionary leader Narendra Modi. This alliance is working to strengthen Modi’s government and to ensure that the next government will have a big voice, and people of Tamil Nadu will have a big representation,” he said. The BJP is committed to setting up an authority to speed up the implementation of the interlinking of rivers. The Congress and the DMK in the last ten years did nothing for interlinking of rivers. However, from 2014, the Modi Government has continuously worked on this. For example, the Godavari-Cauvery link has tremendous potential and can help all southern States, with Tamil Nadu being one of the biggest beneficiaries. Both the Centre and the State government are working to set up a series of solar-powered desalination plants to provide immediate relief to the people of Tamil Nadu especially in the coastal areas by providing drinking water.The Kusum Yojna will be a game changer for farmers who will be encouraged to set up solar power generation in a part of their fields. The solar power will be used to power pumps and the balance power will be fed to the Tamil Nadu power grid so that farmers’ income can increase significantly by the use of land for solar power apart from increasing the crop yield, he said. April 12, 2019center_img SHARE national elections SHARE SHARE EMAIL Published onlast_img read more